QuantiFERON-TB Gold In-Tube

QuantiFERON-TB Gold In-Tube

QFT is an innovative blood test that measures the cell-mediated immune response of TB-infected individuals.



QFT  is an innovative blood test that measures the cell-mediated immune response of TB-infected individuals.

QFT  uses specially designed (1mL) blood collection tubes that are coated with M. tuberculosis specific antigens, along with a negative and a positive control tube.

These TB-specific antigens are encoded within two regions of the M. tuberculosis genome, which are deleted from all BCG strains and most non-tuberculous mycobacterial (NTM) species (with the exception of M. kansasii, M. marinum and M. szulgai).

This makes QFT highly specific for detecting M. tuberculosis infection.

In addition to all the benefits of QuantiFERON TB Gold, the new In-Tube method has the following advantages:

* Minimises blood handling and simplifies the blood stimulation step of QuantiFERON-TB Gold.

* Is highly compatible with automated ELISA platforms, allowing large volume screening.

* The simplified blood stimulation step allows the test to be used in any location. The Blood Collection Tubes are easily transported for ELISA testing. A convenient and cost effective option for blood stimulation, regardless of location, is to use the Cellestis portable incubator.

* High sensitivity (~90%) has been shown in culture confirmed TB patients, exceeding that of the Mantoux test. Specificity is also very high (>98%) even in BCG vaccinated individuals. The In-Tube method has equivalent or higher sensitivity and specificity than that seen with QuantiFERON-TB Gold.

The QuantiFERON-TB Gold In-Tube test has CE Marking and is available for use in Europe, Australia, Canada (approved by Health Canada August 2006), Africa, Middle East and Asia.

Ref/ Pack Sizes:

Med 0590 0301 : QFN-TB Gold Tubes (nil+TB Ag+Mit) : x 100

Med 0594 0201 : QFN-TB Gold Elisa : x 58

Med 0597 0201 : QFN Single patient packs: x 10

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